European Summit on Pharmacology and Toxicology May 04-05, 2020 Vienna, Austria

Tiny, biocompatible nanolaser could function inside living tissues-Nanolaser has potential to treat neurological disorders or sense disease biomarkers

Researchers have developed a tiny nanolaser that can function inside of living tissues without harming them.

Just 50 to 150 nanometers thick, the laser is about 1/1,000th the thickness of a single human hair. At this size, the laser can fit and function inside living tissues, with the potential to sense disease biomarkers or perhaps treat deep-brain neurological disorders, such as epilepsy.

Developed by researchers at Northwestern and Columbia Universities, the nanolaser shows specific promise for imaging in living tissues. Not only is it made mostly of glass, which is intrinsically biocompatible, the laser can also be excited with longer wavelengths of light and emit at shorter wavelengths.

"Longer wavelengths of light are needed for bioimaging because they can penetrate farther into tissues than visible wavelength photons," said Northwestern's Teri Odom, who co-led the research. "But shorter wavelengths of light are often desirable at those same deep areas. We have designed an optically clean system that can effectively deliver visible laser light at penetration depths accessible to longer wavelengths."

The nanolaser also can operate in extremely confined spaces, including quantum circuits and microprocessors for ultra-fast and low-power electronics.

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